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The animal charity has reported a staggering 621 per cent rise in dog ear cropping over the last six years, and have had to deal with a total of 279 reports of the practice made to its emergency hotline.
Ear cropping, where a pooch's ears are surgically altered, or even removed altogether, is illegal in England and Wales under Section 5 of the Animal Welfare Act 2006.
However, in other parts of the world, cropping ears is legal and common practise, with many choosing to crop a pup's ears to make them look more aesthetically pleasing.
The RSPCA has stressed that cropping a pup's ear is in no way beneficial to a dog, and could be detrimental to its development and welfare.
Some dogs can have pain memory and be sensitive to touch around their ears and heads, which can mean they find common everyday routines - such as grooming or putting on a collar or harness - difficult. Others can find it difficult to communicate with other dogs and people, as dogs use their ears to express how they're feeling.
The charity's stark warning about ear cropping comes as it helps rehome two Antolian shepherd dogs that have fallen victim to the cruel practise.
Ezra and Rambo were two of four dogs signed over to RSPCA officers by their previous owners and arrived at the charity's Danaher Animal Home last month.
Danaher animal manager Craig Horsler said of the dogs: "Ezra and Rambo are stunning Anatolian Shepherds. The breed is an ancient guardian breed that was traditionally used in Europe for livestock guarding.
"They are intelligent and loyal and can fit in really well with families so could live with older primary school children.
"Ezra is a gentle, sociable dog and loves the company of other dogs so may be able to live with another dog.
"She's a loving, affectionate dog who loves to be stroked and spend time with people.
"Rambo is a laid-back gentleman but can be strong on the lead and can sometimes be over-excited. He loves human attention and enjoys laying next to you for fuss. He loves to spend time outside and socialises well with other dogs.
"Both dogs are really happy, friendly shepherd's despite the fact that they've had their ears cruelly cropped."
Anyone who suspects someone is cropping their dogs' ears should report this to the RSPCA emergency hotline on 0300 1234 999.
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