Amy Schumer is among the many A-listers to admit they’ve dabbled in Ozempic, but she revealed last year there had been one key reason why she decided to stop.
The drug – also known by its unbranded name of semaglutide - was designed to treat type 2 diabetes, but has also been adopted as a weight loss tool thanks to its ability to reduce appetite.
While some celebs have remained elusive about their use of Ozempic, Schumer, 43, is among those happy to be candid about her experience with the controversial medicine.
Speaking on Watch What Happens Live with Andy Cohen last year, she explained that she’d previously tried it out for herself.
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“Like a year ago, I tried it,” she told host Andy Cohen.
However, the star eventually decided to stop taking the drug, which isn't approved for weight loss in the US by the Food and Drug Administration (FDA), because of the side effects she suffered.
“I was one of those people that felt so sick and couldn’t play with my son,” Schumer, who shares son Gene with husband Chris Fischer, continued.
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“I was so skinny and he’s throwing a ball at me and [I couldn’t].”
According to Ozempic’s official website, possible adverse effects include nausea, stomach pain, constipation, diarrhoea and vomiting.
Schumer said she felt ‘immediately invested’ in the drug before trying it out, but later realised it wasn’t a ‘livable’ option for her.
She also called out other celebs for being cagey about their own dalliance with Ozempic, calling on them to stop ‘lying’.
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“Everyone’s like: ‘Smaller portions,’” the actor said.
“Shut the f*** up. You’re on Ozempic, or one of those things.”
She added: "Just stop. Just be real with the people.”
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James Corden recently shocked fans when he admitted to using Ozempic to lose weight.
"I tried Ozempic," he told SiriusXM.
"And it won't be surprising to you when you look at me now, that it didn't really work."
Corden continued: "I tried it for a bit and then what I realised was I was like, 'Oh no, nothing about my eating has anything to do with being hungry'.
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"All it does is make you feel not hungry. But I am very rarely eating (just because I'm hungry)."
The father-of-three admitted that, while the drug assisted him in his initial weight loss journey, it failed to address the emotional and mental reasons for his harmful relationship with food, claiming he has an 'addictive personality'.
"You are looking at someone who's eaten a king size," he went on.
"And when I say king size, Dairy Milk - one you give someone for Christmas - in a carwash.
"None of that was like, 'Oh, I'm so hungry.' It is not that, it's something else."
Jess Hardiman