• News
  • Life
  • TV & Film
  • Beauty
  • Style
  • Home
  • News
    • Celebrity
    • Entertainment
    • Politics
    • Royal Family
  • Life
    • Animals
    • Food & Drink
    • Women's Health
    • Mental Health
    • Sex & Relationships
    • Travel
    • Real Life
  • TV & Film
    • True Crime
    • Documentaries
    • Netflix
    • BBC
    • ITV
    • Tyla Recommends
  • Beauty
    • Hair
    • Make-up
    • Skincare
  • Style
    • Home
    • Fashion
    • Shopping
  • Advertise
  • Terms
  • Privacy & Cookies
  • LADbible Group
  • LADbible
  • UNILAD
  • SPORTbible
  • GAMINGbible
  • UNILAD Tech
  • FOODbible
  • License Our Content
  • About Us & Contact
  • Jobs
  • Latest
  • Topics A-Z
  • Authors
Facebook
Instagram
X
Threads
TikTok
Submit Your Content
Doctor issues warning as people on weight loss injections discover ‘golden dose’

Home> News

Published 14:23 1 Aug 2025 GMT+1

Doctor issues warning as people on weight loss injections discover ‘golden dose’

People are being warned against using the 'golden dose', also known as the 'fifth dose'

Lucy Devine

Lucy Devine

Featured Image Credit: Getty Stock Photo

Topics: Health, Mounjaro, UK News, News, Ozempic

Lucy Devine
Lucy Devine

Lucy is a journalist working for Tyla. After graduating with a master's degree in journalism, she has worked in both print and online and is particularly interested in fashion, food, health and women's issues. Northerner, coffee addict, says hun a lot.

X

@lucedevine

Advert

Advert

Advert

A doctor has issued a warning to people who use weight loss jabs over the 'golden dose'.

The use of GLP-1 medication, such as Ozempic and Mounjaro, has skyrocketed in the last few years, and work by mimicking hormones that signal your brain to feel full.

It also aids in slowing digestion as both drugs work to slow down the rate at which food leaves the stomach, giving the user that fuller feeling for longer.

Also prescribed to those with type 2 diabetes, the drugs can improve the body’s response to insulin to help regulate blood sugar levels and fat storage.

Advert

While most people use the treatment correctly, one doctor has issued a warning over the 'golden dose' - also known as the 'fifth dose'.

The golden dose refers to extra fluid at the bottom of each injectable pen.

However, to get the most out of each pen, people are using the extra medicine as a 'fifth dose' - but it comes with some pretty big risks.

In fact, social media is filled with people reporting unpleasant side effects from accidentally taking too much of the drug, after miscalculating the dose.

Advert

The use of weight loss jabs has increased recently (Getty Stock Image)
The use of weight loss jabs has increased recently (Getty Stock Image)

Now, one doctor has spoken out about the dose, appearing on This Morning where he answered some questions about what it is and why it's not advisable to take it.

Dr Hussain Al-Zubaidi explained: "The golden dose you talked about is utilising the buffer fluid that's in the injection. So, in order for the injection to give all of its doses and to make sure that every dose contains the full dose, there's a little bit extra, that's there to be wasted.

"People try to utilise that, and there is no evidence base that that is somehow a 'golden dose' or gonna' bring about anything. So be careful."

Advert

Dr Hussain warned against the fifth dose (Getty Stock Photo)
Dr Hussain warned against the fifth dose (Getty Stock Photo)

When co-host Alison Hammond asked exactly how it works, Dr Hussain said: "Essentially, squeezing it out with the final click which isn't there if that makes sense.

"Which just isn't something I would do, because you're now changing the dose and there's a reason why we give those set doses.

"Because they've been studied, they've been looked at, whole ranges get explored and then specific ones get used.

Advert

"And there's a reason why specific doses get used."

People have been taking the 'golden dose' to get the most out of each pen (Getty Stock Photo)
People have been taking the 'golden dose' to get the most out of each pen (Getty Stock Photo)

Tyla has reached out to the manufacturers of Ozempic and Mounjaro for comment.

In response, Novo Nordisk - the manufacturers of Ozempic - said: "Novo Nordisk does not condone, suggest, or encourage misuse of any of our medicines outside of their approved indications.

Advert

"It is important to note that the decision to prescribe these medicines in any dosage should be made by a healthcare professional.

"The approved doses of semaglutide are the only dose strengths that have been studied as maintenance doses in our phase 3 clinical development programs. Whilst there may be a residual amount of medicine left, this does not correspond to a full dose. Any excess solution in the pen should be discarded."

Meanwhile, Elli Lily, which manufactures Mounjaro, said: "The Mounjaro (tirzepatide) KwikPen is designed to deliver a fixed volume of Mounjaro solution at each dose.

"The KwikPen contains sufficient solution to allow for the necessary priming before each injection and the delivery of a total of 4 doses (one dose given weekly for a 28-day supply of medicine).

"Medication will remain in the KwikPen cartridge following the delivery of the 4 fixed doses, however, an additional complete dose cannot be dialled. The KwikPen must be discarded after 4 doses or 30 days after first use."

  • Weight loss jab ‘golden dose’ explained as doctor issues warning to users trying it
  • What actually happens when you ask your doctor about trying weight-loss injections
  • Weight-loss jabs linked to possible fatalities and life-threatening illnesses
  • Adam Lambert explained why he switched from Ozempic to Mounjaro after revealing drastic weight loss

Choose your content:

23 mins ago
an hour ago
16 hours ago
  • Facebook
    23 mins ago

    Charlie Kirk suspected killer’s alarming text exchange after shooting revealed by authorities

    The alleged text messages that Charlie Kirk assassination suspect Tyler Robinson sent have been revealed

    News
  • Samir Hussein/Samir Hussein/WireImage
    an hour ago

    Prince Harry makes very surprising admission after King Charles reunion

    The Duke of Sussex has updated royal fans on what his priorities are after meeting with dad King Charles III

    News
  • CBC Toronto/ Trent Nelson/The Salt Lake Tribune/Getty Images
    16 hours ago

    British father speaks out after being falsely linked to killing of Charlie Kirk amid fake reports

    A father was caught in a horrifying case of mistaken identity following the death of Charlie Kirk

    News
  • Instagram/@meghan
    16 hours ago

    Meghan Markle's unexpected choice of image for Prince Harry's birthday causes major stir

    Prince Harry celebrates his 41st birthday today (Mon 15 Sept)

    News