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Celebs who’ve used Mounjaro as first ever head-to-head trial against Wegovy reveals which one is more effective for weight loss

Home> Entertainment> Celebrity

Updated 14:49 12 May 2025 GMT+1Published 14:45 12 May 2025 GMT+1

Celebs who’ve used Mounjaro as first ever head-to-head trial against Wegovy reveals which one is more effective for weight loss

The controversial medication has been taken by a number of huge-name stars

Rhianna Benson

Rhianna Benson

The results are finally in after two hotly-debated drugs - Mounjaro and Wegovy - were pitted against one another in a new scientific weight loss assessment.

Both medications have hit headlines ceaselessly over the last year or so - particularly when it comes to the entertainment realm - with Wegovy simply being a different brand for the arguably more controversial drug, Ozempic.

Despite traditionally being prescribed to tackle the effects of type 2 diabetes, recent times have seen the drugs used by huge-name stars in a bid to shed a few pounds.

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The weekly injectables are purposed to mimic the GLP-1 hormone, and create signals that make the brain believe a person is full.

Whilst Wegovy also contain semaglutide - an ingredient used to control blood sugar by means of suppressing a person's appetite - Moujaro contains a slightly different ingredient, tirzepatide, which has a similar effect.

Mounjaro was pitted against Wegovy (George Frey/Bloomberg via Getty Images)
Mounjaro was pitted against Wegovy (George Frey/Bloomberg via Getty Images)

The latest study

As we say, the first head-to-head trial against both medications was undertaken recently by manufacturers of Mounjaro, with 750 medically obese participants having taken part.

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With an average weight of 113kg, the group received treatment for 72 weeks, enduring side effects like nausea, vomiting, diarrhoea, and fatigue.

Eventually, it was proven that Mounjaro is more affective than Wegovy in terms of weight loss, with 32 per cent of participants losing a quarter of their body fat, compared to a 16 per cent in the latter group.

Mounjaro patients were also found to have improved blood pressure, blood sugar and cholestrol levels.

It's no wonder, therefore, that so many trimmed down celebrities swear by the medication.

Meghan Trainor recently admitted to taking Mounjaro (Christopher Polk/Billboard via Getty Images)
Meghan Trainor recently admitted to taking Mounjaro (Christopher Polk/Billboard via Getty Images)

Supporting stars

Amongst the countless Hollywood locals that have opened up about administering Mounjaro in recent months is American singer, Meghan Trainor.

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The 'All About The Base' singer shared a post of her new look last month, crediting the drug for having boosted her confidence.

Despite admitting to feeling 'disheartened' by the new focus on her physique - and not her music - lately, the hitmaker admitted she's happy to look and feel 'healthier' for the sake of her two young children.

On a recent episode of The Kardashians, TV socialite Scott Disick also discussed taking Mounjaro with Khloé.

"Everybody that’s got a problem with Mounjaro can suck on my d**k," he declared recently.

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"By the way, they can see my d**k now because, for a minute, you couldn’t. It was tough living that large!"

Earlier this year, comedian Amy Schumer also admitted to taking the drug, after claiming in 2024 that a stint on Ozempic - or Wegovy - left her 'bedridden'.

Scott Disick was open about his Mounjaro use (Jon Kopaloff/FilmMagic for ABA)
Scott Disick was open about his Mounjaro use (Jon Kopaloff/FilmMagic for ABA)

In a new self-fronted Instagram video, the funny-woman revealed she had been prescribed the medication alongside estrogen and progesterone for perimenopause, adding: "It’s not covered by insurance unless you have diabetes or severe obesity, which most of the internet thinks I have.

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"But I’m having a really good experience with it, and I wanted to keep it real with you about that.

"That’s all I have to say, and I’m not gonna talk any s***, I’m not gonna stir the pot."

Featured Image Credit: Tom Cooper/Getty Images for SeriesFest/Getty Stock Image

Topics: Celebrity, Entertainment, Health, Ozempic, US News, Science

Rhianna Benson
Rhianna Benson

Rhianna is an Entertainment Journalist at LADbible Group, working across LADbible, UNILAD and Tyla. She has a Masters in News Journalism from the University of Salford and a Masters in Ancient History from the University of Edinburgh. She previously worked as a Celebrity Reporter for OK! and New Magazines, and as a TV Writer for Reach PLC.

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@rhiannaBjourno

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  • Common Wegovy side effects as weight loss drug surges in popularity in the UK
  • Meghan Trainor leaves fans divided after changing popular song lyric following Mounjaro-induced weight loss
  • Amy Schumer admits she's on new weight loss drug after revealing concerning reason she had to stop taking Ozempic
  • Sharon Osbourne made sad admission about weight loss after revealing worrying side effects caused by Ozempic

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