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Experts issue warning to anyone who has itchy skin as it could be a sign of a rare cancer

Home> Life

Updated 17:16 1 May 2025 GMT+1Published 17:12 1 May 2025 GMT+1

Experts issue warning to anyone who has itchy skin as it could be a sign of a rare cancer

It is not yet known what exactly causes itching

Rhiannon Ingle

Rhiannon Ingle

Experts have issued a warning to anyone who has itchy skin as it could be a symptom of a rare cancer.

The cancer in question is the fifth most common cancer in the whole of the UK, with over 40,000 people being diagnosed with it every year, and it is estimated that as many as one in every 16 men and one in every 22 women will develop it at some point in their lives.

However, the specific type in particular is far more rare.

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It has, like several other cancers, multiple symptoms including weight loss that is unexplained, bruising or bleeding that is unexplained, lumps or swellings, shortness of breath, drenching night sweats, infections that are persistent, recurrent or severe and a fever (38°C or above) that is unexplained.

Additionally, as we say, skin itchiness is named as one of the more common ones but it's important to note that just because you have itchy skin - it doesn't necessarily mean you have cancer.

Itching is a common symptom of some types of cancer (Rawpixel / Getty Images)
Itching is a common symptom of some types of cancer (Rawpixel / Getty Images)

Blood Cancer UK explains that itching is a common symptom of some types of blood cancer, warning on its official website: "If you have blood cancer you might experience itchy skin. Itching can be a symptom of blood cancer or it may be caused by the treatment you are having."

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Some people diagnosed with myeloproliferative neoplasms (MPNs) - which are rare, potentially life-threatening blood cancers that happen when your bone marrow makes too many blood cells - will experience itching, but it is important to note that it can occur with any blood cancer.

MPNs include MPNs polycythaemia vera (PV), essential thrombocythaemia (ET) and the rare myelofibrosis (MF).

The organisation explains that it is currently not yet known what exactly causes itching, but it’s possible it may be triggered by a type of cell called a mast cell releasing a substance called histamine.

It is currently not yet known what exactly causes itching (KATERYNA KON/SCIENCE PHOTO LIBRARY / Getty Images)
It is currently not yet known what exactly causes itching (KATERYNA KON/SCIENCE PHOTO LIBRARY / Getty Images)

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Histamine can affect the activity of small proteins called cytokines, which are known to cause an itchy sensation.

"For some people, taking anti-histamines may help to reduce or get rid of the itch. If your itching is caused by cell activity related to your blood cancer, starting treatment can also lessen your symptoms over time, but this may not be immediate," Blood Cancer UK adds.

The organisation also notes that itchy skin can also be a side effect of some blood cancer treatments as patients may become itchy straight away after starting a new treatment, or the symptoms could come on gradually.

You can find out more about blood cancer here.

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If you’ve been affected by any of these issues and want to speak to someone in confidence, contact Macmillan’s Cancer Support Line on 0808 808 00 00, 8am–8pm seven days a week.

Featured Image Credit: Getty Stock Images

Topics: Skincare, Cancer, Health, Life, Advice

Rhiannon Ingle
Rhiannon Ingle

Rhiannon Ingle is a Senior Journalist at Tyla, specialising in TV, film, travel, and culture. A graduate of the University of Manchester with a degree in English Literature, she honed her editorial skills as the Lifestyle Editor of The Mancunian, the UK’s largest student newspaper. With a keen eye for storytelling, Rhiannon brings fresh perspectives to her writing, blending critical insight with an engaging style. Her work captures the intersection of entertainment and real-world experiences.

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