Hidden MS symptoms to look out for as Christina Applegate reveals first sign of condition she noticed whilst filming Netflix pilot

Here are some hidden MS symptoms to be aware of following Christina Applegate's revealing when the first sign of the condition starts appearing whilst filming.

Applegate, 53, was diagnosed with multiple sclerosis (MS) a few years back in 2021, while working the third and final season of the Netflix comedy-drama, Dead to Me.

According to the NHS, MS is a condition which affects a person's brain and spinal cord.

The Anchorman star recently opened up some more about what it was like when her symptoms first started appearing on set in 2019.

On Tuesday (10 December), she discussed the situation on her Messy podcast, which she co-hosts with Jamie-Lynn Sigler, who also has MS - explaining that she initially put one major symptom down to working too hard on set.

She explained that she was running across a field for a scene for the pilot episode and fell down - which she now recognises as an early sign of her autoimmune condition.

"I remember falling that day," Applegate recalled. "Hi, first sign of MS!"

Her close friend, Liz Feldman, who is also the creator of Dead To Me, was present during the moment and recounted: "I remember you losing your balance a couple of times but it was very hard to figure out.

Christina Applegate has been sharing her health journey with fans following her MS diagnosis in 2021 (Monica Schipper / Staff / Getty Images)

"I remember one time it was like really late at night, we’d been shooting probably 14 or 15 hours, it seemed completely reasonable that anybody would be collapsing."

Applegate also took a moment to thank the show's producers for being so accommodating to her condition, especially when her mobility started declining towards the end of the show.

"That would not happen anywhere else," she praised. "So my gratitude toward you guys being humans - because you should be humans and love other humans! - is, like, I can’t even tell you, that’s not the normal reaction!"

Applegate previously shared the five 'weird' symptoms she ignored before realising she had MS which include; balance issues. speech issues, shaky hands, feeling weak at the knees when walking and having numb toes.

Along with those symptoms, there are also a number of other 'invisible' ones to look out for that people might not realise is the 'unseen side' of the condition.

Applegate's symptoms began to appear while she was filming Dead to Me (Netflix)

The Multiple Sclerosis Trust has also mapped out several symptoms that 'may not be visible to other people'.

These include:

• Anxiety
• Bladder symptoms
• Bowel difficulties
• Cognitive symptoms
• Depression
• Dizziness
• Fatigue
• Pain
• Sexual issues for men and women
• Sight problems

The NHS adds that the conditions may affect people differently, so if you suspect you might have MS, then you should contact your GP.

You can find out more about MS on the official NHS website here.