Amy Schumer had perfect response to concern about her ‘puffier face’ as she revealed reason behind it

Amy Schumer thanked trolls for the 'deliberation about my appearance' as she hit back at comments saying her face was 'puffier than normal'.

Earlier this year, the 43-year-old comedian appeared on The Tonight Show Starring Jimmy Fallon to promote her series Life & Beth, but viewers at home were seemingly more interested in her face, which they kindly pointed out was looking 'puffier' than usual.

The comments continued to roll in on social media commenting on Schumer's appearance, forcing the star to eventually speak out and shut down the chatter.

The comedian opened up about her health (Jamie McCarthy/Getty Images for Good+Foundation)

Posting on Instagram, the Trainwreck actor began: “Thank you so much for everyone's input about my face!"

Going on to agree that yes, her face is 'puffier than usual', the star opened up about her health which she says was responsible for the change in her appearance.

"I have endometriosis, an auto-immune disease that every woman should read about," she hit back.

"There are some medical and hormonal things going on in my world right now but I'm okay."

Perfectly finishing off her response, Schumer added that 'historically women's bodies have barely been studied medically compared to men' and 'a woman doesn't need any excuse for her physical appearance and owes no explanation'.

Mic drop.

Shockingly, his apparently wasn't enough to make trolls zip it, with Schumer later claiming on the Not Skinny But Not Fat podcast that she gets more negative comments about her appearance than her career.

Schumer had the perfect response to the haters (Dipasupil/Getty Images)

“I think they're mad that I'm not thinner, I think they're mad I'm not prettier, and that I still feel like I have a right to speak,” she said.

Luckily, Schumer says she's developed a 'thick skin' over the years working in showbiz and reckons a lot of the hate is down to one thing: misogyny.

The star also previously opened up about her diagnosis of Cushing syndrome which is caused when 'the body has too much of the hormone cortisol for a long time'.

This can result in the body producing cortisol in overdrive, with the main symptoms being a rounded face, high blood pressure and a 'hump' between the shoulders.

Meanwhile, endometriosis is a disease in which tissue similar to the lining of the uterus grows outside the uterus.

If you have been affected by the contents of this article, please find more information and support via Endometriosis UK on their website, or call 0808 808 2227.