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An American news network was broadcasting live from CHI Memorial hospital in Tennessee Valley, USA on Thursday to record medical staff at the hospital receiving the first doses of the historic vaccine.
However, viewers were left startled when critical care unit nurse Tiffany Dover fainted minutes after receiving the injection.
You can watch her response here.
She had previously told reporters about the struggles the hospital had faced treating the numerous patients admitted suffering from Covid-19.
"It's been a hard time. We've persevered through it, but I think this vaccination offers us hope," she told Channel 3.
Tiffany began to feel light-headed around 10 minutes after receiving the first dose, and was forced to walk away from the interview.
"All of my staff... we are excited to get the vaccine. We are in the COVID unit, so therefore... my team will be getting first chances to get the vaccine," she said.
"And I know that it's really ... Sorry, I'm feeling really dizzy," she trailed off.
After a few moments, Tiffany explained that her response was not due to the contents of the vaccine, which was tested on over 43,000 people and is thought to be 95 per cent effective at inoculating people from the deadly coronavirus.
She said she had often passed out as a response to feeling short, sharp pain, telling cameras: "I have a history of having an over-reactive vagal response, and so with that if I have pain from anything, hangnail or if I stub my toe, I can just pass out.
"I felt a little disoriented but I feel fine now, and the pain in my arm is gone."
The UK was the first country to approve the use of the coronavirus vaccine, with those over 80 now starting to receive the jab.
Celebrities such as Prue Leith and Sir Ian McKellen have since received the first of their two doses, with both describing the process as "painless" and "exciting".
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