You can't choose your family but they're often the ones that will have your back come thick or thin.
However, despite an unwavering support network, new research has found that when you fall out with your relatives it can actually put a massive strain on your health.
So if you've found yourself in a screaming match like the Kardashians, be sure to keep a check on your blood pressure.
Research published in the US Journal of Family Psychology discovered that strained relationships with parents, brothers, sisters or other family members may be more harmful impact than a troubled relationship with a partner.
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Doctors said that their findings mean that if someone has a chronic health problem, a negative environment within their family could make their condition even worse.
While many studies often look at long-term effects of an intimate relationship, study lead author Dr Sarah Woods pointed out how, because we are choosing to settle down later on in life, primary family relationships can be more emotionally intense.
Dr Woods, Assistant Professor of family and community medicine at University of Texas Southwestern Medical Centre in the US, explained: "Most often, researchers focus on romantic relationships, especially marriage, presuming they likely have more of a powerful effect on heath.
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"Given changes in how Americans are partnering, waiting longer to marry, if at all, and the lengthier, and possibly more emotion-laden trajectories of family-of-origin relationships, we wanted to compare the strength of associations between family and intimate partners and health over time."
The research team used figures from from more than 2,800 participants in the Midlife Development in the US survey that included a nationally representative sample of adults from 1995 to 2014.
Three groups of data were collected - in 1995 to 1996, 2004 to 2006 and 2013 to 2014. The average participant was 45 years old during the first round.
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Health was measured using the participants' total number of chronic conditions - such as stroke, headaches and stomach trouble - experienced in the 12 months before each of the three data collection times.
The participants also rated their overall health from 'excellent' to 'poor' at each round.
The researchers found that greater family relationship strain was associated with a greater number of chronic conditions and worse health appraisal 10 years later, during the second and third rounds of data collection.
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It was also found that family support has a "significant effect" on quality of life and well-being.
There were no significant effects of intimate partner relationships on health outcomes.
Dr Woods said: "We were honestly stunned that there were zero associations between intimate partner emotional climate and later health."
So next time you find yourself bickering with a relative, rethink that bitchy comment.
Featured Image Credit: E!/Keeping Up With the Kardashians