Giles and Mary have appeared on the show since 2015, and never fail to amuse fans with their witty remarks and adorable relationship.
But the couple's absence sparked concern among viewers, who all took to Twitter to question where they could be.
"Where are Giles and Mary tonight?!?!? Actually fumin [sic]," questioned one person. While somebody else tweeted: "Where were Giles and Mary tonight we missed them they are our favourite couple #Gogglebox."
Another Twitter user declared: "I miss Giles and Mary. I hope they are back next week."
"#Gogglebox ain't the same without Giles, like a fry up without black pudding..." shared another on the social media platform as the episode aired.
Where are the Nutties tonight? I'm missing Giles' observations. #Gogglebox- Lynsey Spence (@Sidekick28) April 19, 2019
@C4Gogglebox Saved the catch up to last night and went to bed depressed - no Giles and Mary - No nutty!!!!- Eamon EM (@eamon_em) April 21, 2019
Thankfully, one of Gogglebox's creators provided answers for fans missing the couple.
Tania Alexander tweeted that the couple were on holiday when filming for Friday's episode took place, but confirmed that they will be back on screens for the next episode of Gogglebox.
Replying directly to one fan questioning why Giles and Mary weren't on their screen, Tani said: "On hols. Back next week."
On hols. Back next week :kissing_heart:- Tania Alexander (@Tanialalexander) April 19, 2019
While she didn't reveal where the Gogglebox stars went on holiday, we can only hope that Giles and Mary provide some hilarious tales from their travels in the next episode.
The married couple appear on the Channel 4 show from their shared home in Wiltshire.
They met at aged 21, when Giles was studying at Wimbledon Art School and Mary was working as a model.
Gogglebox continues on Friday on Channel 4 at 9pm.