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The chilling drama tells the story of serial killer Dennis Nilsen - known as Des - and airs on the channel over three consecutive nights from Monday 14th September at 9pm.
Based on Brian Masters' biography of Nilsen, who murdered at least 15 people before 1983, the TV programme focuses on what happens after Nilsen was captured by police.
The clever drama will tell the story through the prism of three men: Nilsen himself (played by David Tennant), as well as other key characters, Detective Chief Inspector Peter Jay and biographer Brian Masters.
Often known as the 'kindly killer' due to his calm nature and honesty when being interviewed, Nilsen murdered up to 16 boys and men in his North London flat between 1978 and 1983.
The serial killer often preyed on those living off-grid or who were homeless, who often relied on the kindness of strangers.
ITV says: "Des will explore how a man like Nilsen was able to prey on the young and vulnerable in 1980s Britain.
"The series will not only highlight the police investigation and trial but also the effect of the media coverage on public perceptions of the victims at the time, raising questions of just how far have we really come since then."
Starring David Tennant, Daniel Mays as DCI Peter Jay and Jason Watkins as Brian Masters, production began in November 2019.
The creepy drama will also star Ron Cook, Faye McKeever, Chanel Cresswell and Bronagh Waugh.
This newest role is a far cry from Tennant's previous roles, that of 'The Doctor' in Doctor Who and DI Alec Hardy in three series of Broadchurch.
More recently, the actor starred in Channel 4's Deadwater Fell and BBC Two's There She Goes, as well as lockdown drama Staged with Michael Sheen.
The first episode of Des airs on ITV on Monday at 9pm, then at the same time on Tuesday and Wednesday evenings.
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